Child level

Same level

A novel small RNA virus has recently been found in dogs (Woo et al., 2012). The genome sequence appears to be most closely related to the picornaviruses and to have a similar genome organization, except that the P1 and P2/P3 regions are encoded in two ORFs separated by an intergenic region containing an IRES. Its classification remains to be determined.

Accession numbers: JN819202, JN819203 & JN819204.

Genome organisation:

VPg+5'UTR^IRES[1A-1B-1C-1D]IGR^IRES[2A-2B-2C/3A-3B^VPg-3C^pro-3D^pol]3'UTR

IGR, intergenic region
IRES, internal ribosome entry site

References

Woo, P.C., Lau, S.K., Choi, G.K., Huang, Y., Teng, J.L., Tsoi, H.W., Tse, H., Yeung, M.L., Chan, K.H., Jin, D.Y. and Yuen, K.Y. (2012). Natural occurrence and characterization of two internal ribosome entry site elements in a novel virus, canine picodicistrovirus, in the picornavirus-like superfamily. J. Virol. 86: 2797-2808. Epub 2011 Dec 28.