||The genus Cosavirus
consists of five species Cosavirus
and Cosavirus F.
The candidate species, 'Cosavirus C', remains unclassified due to a lack of
full genome sequence data.
Cosaviruses (formerly called
Dekaviruses) have been
identified in the stools of south Asian children (Kapoor et al.,
2008; Holtz et al., 2008; Kapusinszky et al.,
2012). Cosaviruses are most closely related
to members of the
genera, but they lack a leader polypeptide. They possess an 2A NPG¯P
motif, which may or may not be cleaved from VP1. An unusually long
(1,164 nt) 5' UTR contains a type II IRES.
Derivation of name: Cosavirus is from
Search of Cosavirus sequences on GenBank
Holtz, L.R., Finkbeiner, S.R., Kirkwood, C.D. and Wang, D. (2008).
Identification of a novel picornavirus related to cosaviruses in a
child with acute diarrhea. Virology Journal 5: 159;
Kapoor, A., Victoria, J., Simmonds, P.,
Slikas, E., Chieochansin, T., Naeem, A., Shaukat, S., Sharif, S.,
Masroor Alam, M., Angez, M., Wang, C., Shafer, R.W., Zaidi, S. and
Delwart, E. (2008).
A highly prevalent and genetically diversified Picornaviridae genus
in South Asian children. Proc. Natl. Aad. Sci., USA 105:
20482-20487. doi 10.1073 pnas.0807979105.
Kapusinszky, B., Phan, T.G., Kapoor, A. and Delwart, E. (2012).
Genetic diversity of the genus Cosavirus in the family
Picornaviridae: a new species, recombination, and 26 new genotypes.
PLoS One. 7(5):e36685. Epub 2012 May 16.