HEV-A Prototypes

Serotype	Strain	Origin	Year	Illness	Source	Reference
CV-A2	Fleetwood	Delaware	1947	Paralytic illness	stools	Sickles and Dalldorf, 1949
CV-A3	Olson	New York	1948	Aseptic meningitis	stools	Sickles and Dalldorf, 1949
CV-A4	High Point	North Carolina	1950	-	sewage from a polio community	Melnick, 1950
CV-A5	Swartz	New York	1950	Poliomyelitis	stools	Dalldorf and Sickles, 1953
CV-A6	Gdula	New York	1949	Aseptic meningitis	stools	Dalldorf et al., 1949
CV-A7	Parker	New York	1949	Aseptic meningitis	stools	Dalldorf et al., 1949
CV-A8	Donovan	New York	1949	Poliomyelitis	stools	Dalldorf et al., 1949
CV-A10	Kowalik	New York	1950	Aseptic meningitis	stools	Dalldorf et al., 1949
CV-A12	Texas-12	Texas	1948	-	flies from a polio community	Melnick, 1950
CV-A14	G-14	South Africa	1950	none	stools	Gear
CV-A16	G-10	South Africa	1951	none	stools	Gear
EV-71	BrCr	California	1970	Aseptic menigitis; HFMD	stools	Schmidt et al., 1974
All prototypes were isolated from stools except CV-A4 (sewage from a polio community); CV-A12 (flies from a polio community).

References

Dalldorf et al., 1949 (J. exp. Med. 89: 567)

Sickles and Dalldorf, 1949 (Proc. Soc. exp. Biol. Med. 72: 30)

Dalldorf and Sickles, 1953 (In: Diagnostic Procedures for Virus and Rickettsial Diseases 2nd Edition. Am. Public Health Assoc., New York, p.153)

Melnick, 1950 (Bull. N.Y. Acad. Med. 26: 342)

Curnen

Sickles

Gear

Huebner

Lennette

Lennette et al., 1958 (Am. J. Hyg. 68: 272)

Mirkovic et al., 1974 (Intervirol. 4: 119-127)

Sickles et al., 1959 (Proc. Soc. exp. Biol. Med. 102: 742-743)

Abraham and Cheever, 1963. (PSEBM 112: 981)