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 Kobuvirus

Child level

Aichivirus A
Aichivirus B
Aichivirus C
"Aichivirus D"
"Aichivirus E"
"Aichivirus F"
Caprine kobuvirus
European roller kobuvirus 1
Unassigned kobuviruses

Same level

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  The genus Kobuvirus consists of three species, Aichivirus A (formerly Aichi virus), Aichivirus B (formerly Bovine kobuvirus) and  Aichivirus C.

The species Aichivirus A consists of four types: Aichi virus 1, canine kobuvirus 1, feline kobuvirus 1 and murine kobuvirus 1.

The species Aichivirus B consists of three types: bovine kobuvirus 1, ferret kobuvirus 1 & ovine kobuvirus 1.

The species Aichivirus C consists of a single type: porcine kobuvirus 1.

Caprine kobuvirus, cattle kobuvirus and European roller kobuvirus may represent three further candidate species.

Other kobu-like viruses have been identified in bats and rabbits.

Search for Kobuvirus sequences on GenBank

Genome organisation

Aichivirus A (Aichi virus 1, canine kobuvirus 1, feline kobuvirus 1 & murine kobuvirus 1):

VPg+5'UTRIRES-V[L/1AB-1C-1D/2AH-Box/NC-2B-2C/3A-3BVPg-3Cpro-3Dpol]3'UTR-poly(A)

Aichivirus B (bovine kobuvirus 1, ferret kobuvirus 1 & ovine kobuvirus 1):

VPg+5'UTRIRES-V[L/1AB-1C-1D/2AH-Box/NC-2B-2C/3A-3BVPg-3Cpro-3Dpol]3'UTR-poly(A)

Aichivirus C (porcine kobuvirus 1):

VPg+5'UTRIRES-IV[L/1AB-1C-1D/2AH-Box/NC-2B-2C/3A-3BVPg-3Cpro-3Dpol]3'UTR-poly(A)


3A polypeptide

Recently, Greninger et al. (2012) have report that the N-terminal glycines of Aichi virus, bovine kobuvirus and human salivirus (klassevirus) are myristoylated despite not having an N-terminal canonical myristoylation motif (GxxxT/S).

References

Greninger, A.L., Knudsen, G.M., Betegon, M., Burlingame, A.L. and Derisi, J.L. (2012). The 3A protein from multiple picornaviruses utilizes the golgi adaptor protein ACBD3 to recruit PI4KIIIβ. J Virol. 86: 3605-3616. Epub 2012 Jan 18.

Current taxonomy
Genus: Kobuvirus
   
  Species:  Aichivirus A (4 types)
     type: Aichi virus 1
       type: feline kobuvirus 1
       type: canine kobuvirus 1
       type: murine kobuvirus 1
  Species:  Aichivirus B (3 types)
        type: bovine kobuvirus 1
        type: ferret kobuvirus 1
        type: sheep kobuvirus 1
  Species:  Aichivirus C (1 type)
       type: porcine kobuvirus 1
   
  unassigned: caprine kobuvirus 1
unassigned: cattle kobuvirus 1 & 2
  unassigned: European roller kobuvirus 1
   
   

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