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The genus Kobuvirus consists of three species,
Aichivirus A
(formerly Aichi virus),
Aichivirus B
(formerly Bovine kobuvirus) and
Aichivirus C (aka
porcine kobuvirus).
Recently, two other kobuviruses,
Canine kobuvirus 1 and
Murine kobuvirus 1, have
been described and probably belong to the species
Aichivirus A.
Recently, other kobu-like viruses have been identified in
bats.
Search for Kobuvirus
sequences on GenBank
Genome organisation
Aichi virus 1, bovine kobuvirus 1, canine kobuvirus 1 & murine kobuvirus
1:
VPg+5'UTRIRES-V[L/1AB-1C-1D/2AH-Box/NC-2B-2C/3A-3BVPg-3Cpro-3Dpol]3'UTR-poly(A)
Porcine kobuvirus 1:
VPg+5'UTRIRES-IV[L/1AB-1C-1D/2AH-Box/NC-2B-2C/3A-3BVPg-3Cpro-3Dpol]3'UTR-poly(A)
3A polypeptide
Recently, Greninger et al. (2012) have report that the N-terminal
glycines of Aichi virus, bovine kobuvirus and human salivirus (klassevirus)
are myristoylated despite not having an N-terminal canonical myristoylation motif (GxxxT/S).
References
Greninger, A.L., Knudsen, G.M., Betegon, M., Burlingame, A.L. and Derisi,
J.L. (2012). The 3A protein from multiple picornaviruses utilizes the
golgi adaptor protein ACBD3 to recruit PI4KIIIβ. J Virol. 86: 3605-3616.
Epub 2012 Jan 18.
Current taxonomy
| Genus:
Kobuvirus |
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Species: Aichivirus
A
(3 types) |
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type: Aichi virus 1 |
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type: canine kobuvirus 1 |
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type: murine kobuvirus 1 |
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Species:
Aichivirus B
(2 types) |
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type: bovine kobuvirus 1 |
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type: sheep kobuvirus 1 |
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Species:
Aichivirus C (1 type) |
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type: porcine kobuvirus 1 |
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Fig. 1. Phylogenetic
tree (Neighbor-joining) showing the
relationships between the kobuviruses
(P1 amino acid sequences).
Fig. 2.
Phylogenetic tree (Neighbor-joining)
showing the
relationships between
the
kobuviruses
and newly recognised
viruses of humans and
wild birds (P1 amino
acid sequences).
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