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The genus Parechovirus is comprised of two species, Parechovirus A (formerly named Human parechovirus) and Parechovirus B (formerly named Ljungan virus). A new virus, Sebokele virus 1, from rodents may represent a third species in the genus. A fourth virus, ferret parechovirus has recently been described (Smits et al., 2013).

Search for Parechovirus sequences on GenBank

Genome organisation

Human parechovirus:

VPg+5'UTR^IRES-II[1AB-1C-1D/2A^H-Box/NC-2B-2C/3A-3B^VPg-3C^pro-3D^pol]3'UTR-poly(A)

Ljungan virus / Sebokele virus:

VPg+5'UTR^IRES-II[1AB-1C-1D?2A^npgp/2A^H-Box/NC-2B-2C/3A-3B^VPg-3C^pro-3D^pol]3'UTR-poly(A)

Ferret parechovirus:

VPg+5'UTR^IRES-IV[1AB-1C-1D?2A^npgp/2A^H-Box/NC-2B-2C/3A-3B^VPg-3C^pro-3D^pol]3'UTR-poly(A)

Fig. 1. Phylogenetic tree (Neighbor-joining) showing the relationships between the parechoviruses
(P1 amino acid sequences)