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  Picornavirus genera can be phylogenetically clustered into 'supergroups' (SG). These would be the equivalent of subfamilies once formally designated.

SG1: Aphthovirus, Bopivirus, Cardiovirus, Cosavirus, Erbovirus, Hunnivirus, Mischivirus, Mosavirus, Senecavirus, Teschovirus and Torchivirus.

SG2: Dicipivirus
, Gallivirus, Kobuvirus, Megrivirus, Oscivirus, Passerivirus, Rosavirus, Sakobuvirus, Salivirus and Sicinivirus.

SG3: Enterovirus, Rabovirus and Sapelovirus.

SG4: Aalivirus,
Aquamavirus, Avihepatovirus, Avisivirus, Crohivirus, Kunsagivirus, Limnipivirus, Orivirus, Parechovirus, Pasivirus, Potamipivirus and Shanbavirus.

SG5:
Hepatovirus and Tremovirus.

SG6: Harkavirus.


Currently ungrouped genera:
Ampivirus.


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