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VIPERdb - Virus
Particle Explorer
Genus: Rhinovirus
| HRV-14 5-fold axis view |
HRV-14 2-fold axis view |
HRV-14 3-fold axis view |
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| Virus
|
PDB no. |
Description [EMBL
accession no.] |
Reference
|
|
HRV-1A |
1R1A
|
20601 (Ohio) [nt
sequence] |
Kim et al., 1989
|
|
2HWD
|
complexed with the
antiviral agent WIN56291 |
|
|
2HWF
|
complexed with the
antiviral agent R61837 |
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2HWE
|
complexed with the
antiviral agent WIN54954 |
|
|
HRV-2 |
1FPN |
Capsid |
|
|
2HRV |
2A protease |
Petersen et al.,
1999 |
| 1CQQ |
3C protease
|
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| HRV-3
|
1RHI |
? [U60874] |
Zhao et al.,
1996 |
|
HRV-14
|
4RHV
|
1059 (South
Carolina/59) [K02121,
K01087,
L05355]
|
Rossmann et al.,
1985 |
|
1HRI
|
complex with antiviral
agent sch 38057 |
|
|
1HRV
|
complexed with sdz
35-682 |
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1R08
|
complex with antiviral
agent WIN viii$ |
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1R09
|
complex with antiviral
agent WIN R61837 |
|
|
1RMU
|
(mutant with cys 1 199
replaced by tyr) (/c199y$ in chain 1) |
|
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1RUC
|
mutation: n(1)105s;
heterogen: antiviral agent WIN 52035 |
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1RUD
|
mutation: n(1)105s;
heterogen: antiviral agent WIN 52084 |
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1RUE
|
mutation: n(1)219a;
heterogen: antiviral agent WIN 52035 |
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1RUF
|
mutation: n(1)219a
|
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1RUG
|
mutation: n(1)219s;
heterogen: antiviral agent WIN 52035 |
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1RUH
|
mutation: n(1)219s;
heterogen: antiviral agent WIN 52084 |
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1RUI
|
mutation: s(1)223g;
heterogen: antiviral agent WIN 52084 |
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1RUJ
|
mutation: s(1)223g
|
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2HWB
|
mutant with ile 2 170
replaced by val 2 (i(2 170)v) complexed with the antiviral agent WIN
56291 |
|
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2HWC
|
mutant with ile 2 170
replaced by val 2 (i(2 170)v) complexed with the antiviral agent WIN
54954 |
|
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2R04
|
complex with antiviral
agent WIN iv$ |
|
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2R06
|
complex with antiviral
agent WIN vi$ |
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2R07
|
complex with antiviral
agent WIN vii$ |
|
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2RM2
|
complex with antiviral
agent WIN ii(s/r)$ |
|
|
2RMU
|
(mutant with val 1 188
replaced by 2 leu) (/v188l$ in chain 1) |
|
|
2RR1
|
complex with antiviral
agent WIN i(r)$ |
|
|
2RS1
|
complex with antiviral
agent WIN i(s)$ |
|
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2RS3
|
complex with antiviral
agent WIN iii(s)$ |
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2RS5
|
complex with antiviral
agent WIN v(s)$ |
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| HRV-14 |
1NCQ |
HRV14 WHEN COMPLEXED
WITH PLECONARIL |
Zhang et al. |
| HRV-14
|
N/A
|
3C proteinase
|
Matthews et al.,
1994 |
| HRV-14
|
1IK1
|
Solution structure of
an RNA hairpin from HRV-14 |
|
| HRV-16
|
2RHN
|
11757 (Washington
DC/60) [L24917]
|
Oliviera et al.,
1993; Hadfield et al., 1997 |
| HRV-16 |
1ND2 |
|
Zhang et al. |
| HRV-16 |
1NCR |
HRV16 WHEN COMPLEXED
WITH PLECONARIL |
Zhang et al. |
References
Hadfield, A.T., Lee, W.,
Zhao, R., Oliveira, M.A., Minor, I., Rueckert, R.R. and Rossmann, M.G.
(1997). The refined structure of human rhinovirus 16 at 2.15 A resolution:
implications for the viral life cycle. Structure 15: 427-441.
Hansen, J.L., Long, A.M.
and Schultz, S.C. (1997). Structure of the RNA-dependant RNA polymerase of
poliovirus. Structure 5: 1109-????.
Kim, S., Smith, T.J.,
Chapman, M.S., Rossmann, M.G., Pevear, D.C., Dutko, F.J., Felock, P.J.,
Diana, G.D. and McKinlay, M.A. (1989). Crystal structure of human rhinovirus
serotype 1A (HRV1A). J. Mol. Biol. 210: 91-111.
Matthews, D.A., Smith,
W.W., Ferre, R.A., Condon, B., Budahazi, G., Sisson, W., Villafranca, J.E.,
Janson, C.A., McElroy, H.E., Gribskov, C.L. and Worland, S. (1994).
Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide
fold, RNA-binding site, and means for cleaving precursor polyprotein. Cell
77: 761-771.
Oliviera, M.A., Zhao, R.,
Lee, W-M., Kremer, M.J., Minor, I., Rueckert, R.R., Diana, G.D., Pevear,
D.C., Dutko, F.J., McKinlay, M.A. and Rossmann, M.G. (1993). The structure
of human rhinovirus 16. Structure 1: 51-68.
Rossmann, M.G., Arnold, E.,
Erickson, J.W., Frankenberger, E.A., Griffith, J.P., Hecht, H.-J., Johnson,
J.E., Kamer, G., Luo, M., Mosser, A.G., Rueckert, R.R., Sherry, B. and
Vriend, G. (1985). Structure of a human common cold virus and functional
relationship to other picornaviruses. Nature 317: 145-153.
Zhao, R., Pevear, D.C.,
Kremer, M.J., Giranda, V.L., Kofron, J., Rossmann, M.G. and Kuhn, R.J.
(1996). The structure of human rhinovirus 3 at 3.0 A resolution. Structure
4: 1205-1220.
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