| |
Genus: Aphthovirus
Species: Bovine rhinitis A virus
Serotype: bovine rhinitis A
virus 1
(formerly bovine rhinovirus 1) |
|
| 5' UTR |
L |
VP4 |
VP2 |
VP3 |
VP1 |
2A |
2B |
2C |
3A |
3B |
3C |
3D |
3' UTR |
|
Serotype: bovine rhinitis A virus 2
(formerly bovine rhinovirus 3) |
|
| 5' UTR |
L |
VP4 |
VP2 |
VP3 |
VP1 |
2A |
2B |
2C |
3A |
3B |
3C |
3D |
3' UTR |
|
(White areas indicate genes which haven't yet been
sequenced completely;
grey areas are where only partial sequences exist)
| Virus |
Strain |
Region |
Length |
Accession No. |
Reference |
Comments |
Bovine rhinitis A virus 1 (BRAV-1)
|
| BRAV-1 |
bov/RS 3x/UK/c.1969 |
CG(p) |
7267 |
KT948520 |
Knowles, 2005; Piccone et
al., 2010;
Rai et al., 2016 |
5' end missing |
| BRAV-1 |
bov/SD-1/GER/c.1962 |
CG(p) |
|
n/a |
Piccone et al., 2010 |
5' end missing |
|
CG(p) |
7245 |
KP236128 |
Hause et al., 2015 |
5' end missing |
|
CG(p) |
7253 |
KJ608370 |
Hwang
et al., unpub. |
5' end missing |
| BRAV-1 |
bov/BSRI4/USA/2013 |
CG(p) |
7207 |
KP264974 |
Ng et al., 2015 |
5' end missing |
| BRAV-1 |
USII/02/USA/2015 |
CG(p) |
7207 |
KU159364 |
Mitra et al., 2016 |
5' end missing |
| BRAV-1 |
BS16-2/USA/2015 |
CG(p) |
6840 |
KU159362 |
Mitra et al., 2016 |
5' end missing |
| BRAV-1 |
bov/CHN1_LZ01/China/2020 |
CG(p) |
6951 |
MZ004694 |
Zhou, unpub. |
5' & 3' end missing |
| BRAV-1 |
bov/CHN1_LZ10/China/2020 |
CG(p) |
6951 |
MZ004695 |
Zhou, unpub. |
5' & 3' end missing |
| BRAV-1 |
bov/CHN1_LZ11/China/2020 |
CG(p) |
6951 |
MZ004696 |
Zhou, unpub. |
5' & 3' end missing |
| |
|
|
|
|
|
|
Bovine rhinitis A virus 2 (BRAV-2)
|
| BRAV-2 |
H-1/JPN/c.1984 |
CG(p) |
7250 |
JN936206 |
Knowles, 2005; Piccone et
al., 2010;
Knowles & Wadsworth, unpub. |
5' end missing |
| BRAV-2 |
140032-1/USA/2013 |
CG(p) |
7235 |
KP236129 |
Hause et al., 2015 |
5' end missing |
| BRAV-2 |
MexB15/Mexico/2015 |
CG(p) |
7030 |
KU159363 |
Mitra et al., 2016 |
5' end missing |
| |
|
|
|
|
|
|
Bovine rhinitis A virus 3 (BRAV-3) - candidate new type
|
| BRAV-3 |
bov/NSWL6.1/AUS/2019 |
CG(p) |
6845 |
OP020162 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/NSWL12/AUS/2019 |
CG(p) |
7215 |
OP020163 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/NSWL15/AUS/2019 |
CG(p) |
7280 |
OP020164 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/NSWL4/AUS/2019 |
CG(p) |
7223 |
OP020165 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/NSWL9/AUS/2019 |
CG(p) |
7224 |
OP020166 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/NSWL13/AUS/2019 |
CG(p) |
7367 |
OP020167 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/NSWL3/AUS/2019 |
CG(p) |
7221 |
OP020168 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/NSWL10/AUS/2019 |
CG(p) |
7024 |
OP020169 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/NSWL6/AUS/2019 |
CG(p) |
6849 |
OP020170 |
Brito et al., unpub. |
5' & 3' end missing |
| BRAV-3 |
bov/NSWL13.1/AUS/2019 |
CG(p) |
6799 |
OP020171 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/NSWL11/AUS/2019 |
CG(p) |
5224 |
OP020172 |
Brito et al., unpub. |
5' & 3' end missing |
| BRAV-3 |
bov/NSWL8/AUS/2019 |
CG(p) |
7312 |
OP020173 |
Brito et al., unpub. |
5' end missing |
| BRAV-3 |
bov/ASRA5/AUS/2011 |
5'UTR(p)-2B(p) |
3514 |
OQ348269 |
Ambrose et al., unpub. |
|
| |
|
|
|
|
|
|
CG = complete genome
(p) = partial gene sequence
n/a = not available |
Hause, B.M., Collin, E.A., Anderson, J., Hesse, R.A.
and Anderson, G. (2015). Bovine rhinitis viruses are common in U.S.
cattle with bovine respiratory disease. PLoS One 10(3):e0121998.
Knowles, N.J. (2005). Molecular identification of all
three bovine rhinovirus serotypes as members of the genus Aphthovirus.
EUROPIC 2005: XIIIth Meeting of the European Study Group on the
Molecular Biology of Picornaviruses, Lunteren, The Netherlands, 23-29th
May 2005. Abstract A18.
Mitra, N., Cernicchiaro, N., Torres, S., Li, F. and
Hause, B.M. (2016). Metagenomic characterization of the virome
associated with bovine respiratory disease in feedlot cattle identified
novel viruses and suggests an etiologic role for influenza D virus. J.
Gen. Virol. 2016 May 5. doi: 10.1099/jgv.0.000492. [Epub ahead of print]
Ng, T.F., Kondov, N.O., Deng, X., Van Eenennaam, A.,
Neibergs, H.L. and Delwart, E. (2015). A metagenomics and case-control
study to identify viruses associated with bovine respiratory disease. J.
Virol. 89: 5340-5349.
Piccone, M.E., Wadsworth, J., Kramer, E., Pauszek,
S.J., Knowles, N.J. and Rieder, E. (2010). Sequence analysis and
molecular features of bovine rhinovirus types 1 and 3 and their
taxonomic position in the Aphthovirus genus. EUROPIC 2010, St.
Andrews, Scotland, 11-16 September 2010.
Rai, D.K., Lawrence, P., Pauszek, S.J., Piccone, M.E.,
Knowles, N.J. and Rieder, E. (2016). Bioinformatics and molecular
analysis of the evolutionary relationship between bovine rhinitis A
viruses and foot-and-mouth disease virus. Bioinform. Biol. Insights 9(Suppl
2): 43-58.
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